Depends what you want or mean by “good”. Remember, you can’t make a silk purse out of a sow’s ear. No amount of cooking is going to turn flavorless junk like bottom round into filet, or chuck into ribeye. But, you can make some good thin slice roast beef (short cook time - 4-6 hours) or pot roast (long cook 24-36 hours) out of chuck. Bottom round will always be dog food though.